Modeling And Control For Robotic Assistants: Single And Multi-Robot Manipulation

As advances are made in robotic hardware, the complexity of tasks they are capable of performing also increases. One goal of modern robotics is to introduce robotic platforms that require very little augmentation of their environments to be effective and robust. Therefore the challenge for a roboticist is to develop algorithms and control strategies that leverage knowledge of the task while retaining the ability to be adaptive, adjusting to perturbations in the environment and task assumptions. This work considers approaches to these challenges in the context of a wet-lab robotic assistant. The tasks considered are cooperative transport with limited communication between team members, and robot-assisted rapid experiment preparation requiring pouring reagents from open containers useful for research and development scientists. For cooperative transport, robots must be able to plan collision-free trajectories and agree on a final destination to minimize internal forces on the carried load. Robot teammates are considered, where robots must reach consensus to minimize internal forces. The case of a human leader, and robot follower is then considered, where robots must use non-verbal information to estimate the human leader\u27s intended pose for the carried load. For experiment preparation, the robot must pour precisely from open containers with known fluid in a single attempt. Two scenarios examined are when the geometries of the pouring and receiving containers and behaviors are known, and when the pourer must be approximated. An analytical solution is presented for a given geometry in the first instance. In the second instance, a combination of online system identification and leveraging of model priors is used to achieve the precision-pour in a single attempt with considerations for long-term robot deployment. The main contributions of this work are considerations and implementations for making robots capable of performing complex tasks with an emphasis on combining model-based and data-driven approaches for best performance

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Nonmetallized composite propellant combustion

An experimental investigation of nonmetallized composite propellant combustion in standard and high acceleration environments was made. Pressed ammonium perchlorate (AP) pellets of varying purity, AP/binder sandwich burners, and propellant strands were employed. AP/binder sandwich burners where studied in an optically equipped centrifuge and color schlieren were taken in a conventional combustion bomb. Ascast and dewetted propellants were used to study the effect of preferential interfacial reactions on burning rate acceleration sensitivity. Results are discussed for the effects of acceleration, pressure, AP purity, and propellant composition on the burning rate. (Author)Naval Ordnance Systems Command, ORD TASK 331 007/551 l/UF 19-332-303http://archive.org/details/nonmetallizedcom00net